The localisation of oskar mRNA to the posterior of the Drosophila oocyte defines where the abdomen and germ cells form in the embryo.Kinesin 1 transports oskar mRNA to the oocyte posterior along a polarised microtubule cytoskeleton that grows from non-centrosomal microtubule organising centres (ncMTOCs) along the anterior/lateral cortex.Here, we sh
Multicellular organisms rely on intercellular communication to regulate important cellular processes critical to life.To further our understanding of those processes there is a need to scrutinize dynamical signaling events and their functions in both cells and organisms.Here, we report a method and provide MATLAB code that analyzes time-lapse micro
Abstract Background Appendicectomy specimens removed from patients with suspected acute appendicitis often appear macroscopically normal but histopathological analysis of these cases may reveal a more sinister underlying pathology.We evaluated histopathological reports of 1225 appendicectomy specimens at the Norfolk and Norwich University Hospital